A 72-year-old man, Robert Brown, has been diagnosed with chronic myeloid leukemia. Robert has been told he has less than 1 year to live. His oncologist says that stem cell transplantation may help him. He refuses any treatment. His spouse is begging him to please attempt the stem cell transplantation. After testing, his 23-year-old daughter is found to be the best match for him. Robert, however, still does not want to undergo the treatment and refuses to let his daughter be the donor. No other match is found.

1. What is the prognosis for Robert if he is the “typical” case of chronic myeloid leukemia? Identify the prognosis should he agree to the stem cell transplant.

2. What suggestions, if any, do you have for his spouse and daughter?

3. If his daughter were to become a donor for Robert, what preparation would she need?

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